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CHLORIDE CHANNELS, ATP GATED CFTR
Descriptors Found:
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DeCS
Descriptor
English
:
Cystic Fibrosis Transmembrane Conductance Regulator
Descriptor
Spanish
:
Regulador de Conductancia de Transmembrana de Fibrosis Quística
Descriptor
Portuguese
:
Regulador de Condutância Transmembrana em Fibrose Cística
Synonyms
English
:
Chloride channels, ATP-gated CFTR
Chloride channels, ATP gated CFTR
Protein, CFTR
CFTR Protein
Tree Number:
D12.776.157.530.100.304.500
D12.776.157.530.400.175.125
D12.776.157.530.450.074.500.500.500.500
D12.776.543.550.450.175.125
D12.776.543.585.100.304.500
D12.776.543.585.400.175.125
D12.776.543.585.450.074.500.500.500.500
Definition
English
:
A chloride channel that regulates secretion in many exocrine
tissues
. Abnormalities in the CFTR gene have been shown to cause
cystic fibrosis
. (Hum Genet 1994;93(4):364-8)
History Note
English
:
96; was CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (NM) 1989-95
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
32784
Unique Identifier:
D019005
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS